Epidermodysplasia Verruciformis, also known as Tree Bark Syndrome, is an inherited skin disorder characterized by eruptions of wart-like lesions that may occur anywhere on the body. One type of lesions are reddish brown and have scaly surfaces and irregular borders; while the second type are seen on sun-exposed skin and are often slightly raised, brown colored lesions resembling tree bark.

These lesions are caused by infection with a subtype of human papillomavirus (HPV). In general, this virus does not cause any lesions but in people with Epidermodysplasia Verruciformis, the virus causes these lesions. A major concern for these patients is that the disorder may turn into skin cancers. There is no known cure for this disorder. It is managed through medication, surgery and counseling.

source